abstract：:Besides their well-known function in cellular bioenergetics, the role of mitochondria in signaling regulation of cells homeostasis and survival has been uncovered during the past few decades. Possessing an independent genome and a unique genetic code, mitochondria biosynthesize protective stress response factors, the ...

journal_title：Cell and tissue research

authors： Popov LD

更新日期：2019-08-01 00:00:00

abstract：:The solute carrier (SLC) group of membrane transport proteins includes about 400 members organized into more than 50 families. The SLC family that comprises nucleoside-sugar transporters is referred to as SLC35. One of the members of this family is SLC35F1. The function of SLC35F1 is still unknown; however, recent stu...

journal_title：Cell and tissue research

authors： Farenholtz J,Artelt N,Blumenthal A,Endlich K,Kroemer HK,Endlich N,von Bohlen Und Halbach O

更新日期：2019-08-01 00:00:00

abstract：:Dental caries is a chronic, infectious, and destructive disease that allows bacteria to break into the dental pulp tissue. As caries-related bacteria invade the human dentinal tubules, odontoblasts are the first line of dental pulp that trigger the initial inflammatory and immune responses. DNA methylation is a key ep...

journal_title：Cell and tissue research

authors： Meng R,Li D,Feng Z,Xu Q

更新日期：2019-06-01 00:00:00

abstract：:In the current experiment, the combined regime of resveratrol and a Wnt-3a inhibitor, sulindac, were examined on the angiogenic potential of cancer stem cells from human colon adenocarcinoma cell line HT-29 during 7 days. Cancer stem cells were enriched via a magnetic-activated cell sorter technique and cultured in en...

journal_title：Cell and tissue research

authors： Pouyafar A,Rezabakhsh A,Rahbarghazi R,Heydarabad MZ,Shokrollahi E,Sokullu E,Khaksar M,Nourazarian A,Avci ÇB

更新日期：2019-06-01 00:00:00

abstract：:Lysozyme is one of the most prominent antimicrobial peptides and has been identified from many mammalian species. However, this enzyme has not been studied in the order Insectivora, which includes the most primitive placental mammals. Here, we done the lysozyme cDNA from Suncus murinus (referred to as suncus, its labo...

journal_title：Cell and tissue research

authors： Takemi S,Ojima S,Tanaka T,Sakai T,Sakata I

更新日期：2019-06-01 00:00:00

abstract：:Neuropeptide F in invertebrates is a homolog of neuropeptide Y in mammals and it is a member of FMRFamide-related peptides. In arthropods, such as insects, there are two types of neuropeptide F comprising long neuropeptide F (NPF) and short neuropeptide F (sNPF). Both NPFs are known to play a crucial role in the regul...

journal_title：Cell and tissue research

authors： Thongrod S,Wanichanon C,Sobhon P

更新日期：2019-06-01 00:00:00

abstract：:We have previously shown that the chromogranin A (CgA)-derived peptide catestatin (CST: hCgA352-372) inhibits nicotine-induced secretion of catecholamines from the adrenal medulla and chromaffin cells. In the present study, we seek to determine whether CST regulates dense core (DC) vesicle (DCV) quanta (catecholamine ...

journal_title：Cell and tissue research

authors： Sahu BS,Mahata S,Bandyopadhyay K,Mahata M,Avolio E,Pasqua T,Sahu C,Bandyopadhyay GK,Bartolomucci A,Webster NJG,Van Den Bogaart G,Fischer-Colbrie R,Corti A,Eiden LE,Mahata SK

更新日期：2019-04-01 00:00:00

abstract：:Tissue lectins appear to be involved in a broad range of physiological processes, as reflected for the members of the family of galectins by referring to them as adhesion/growth-regulatory effectors. In order to clarify the significance of galectin presence, key challenges are to define their binding partners and the ...

journal_title：Cell and tissue research

authors： García Caballero G,Schmidt S,Schnölzer M,Schlötzer-Schrehardt U,Knospe C,Ludwig AK,Manning JC,Muschler P,Kaltner H,Kopitz J,Gabius HJ

更新日期：2019-03-01 00:00:00

abstract：:Exposure to nicotine in smoking contributes to most unexplained male infertility but the mechanisms remain to be fully elucidated. Zinc (Zn) is an essential trace element in normal growth, development and reproduction. Zinc oxide nanoparticles (ZnONPs) are well-known antioxidants. Therefore, this work was designed to ...

journal_title：Cell and tissue research

authors： Mohamed DA,Abdelrahman SA

更新日期：2019-02-01 00:00:00

abstract：:To gain a better understanding of the neuroplasticity of sympathetic neurons during postnatal ontogenesis, the distribution of neuronal nitric oxide synthase (nNOS) immunoreactivity was studied in sympathetic preganglionic neurons (SPN) in the spinal cord (Th2 segment) of female Wistar rats at different ages (newborn,...

journal_title：Cell and tissue research

authors： Moiseev KY,Romanova IV,Masliukov AP,Masliukov PM

更新日期：2019-02-01 00:00:00

abstract：:Obesity induces metabolic disorders such as type 2 diabetes, hypertension, and cardiovascular diseases and has become a global health concern. Recent studies imply that fat accumulation in nonadipose tissue correlates with metabolic disorders. However, there are no suitable animal models to evaluate this phenomenon. T...

journal_title：Cell and tissue research

authors： Nakamura T,Ichii O,Irie T,Kouguchi H,Sotozaki K,Chihara M,Sunden Y,Nagasaki KI,Tatsumi O,Elewa YHA,Kon Y

更新日期：2019-02-01 00:00:00

abstract：:Sex pheromones orient male moths toward conspecific female moths; the presence of visual information modulates this behavior. In the current study, we explore candidate neuronal pathways for the interaction between vision and the locomotor signal for pheromone orientation. We describe the connectivity between visual n...

journal_title：Cell and tissue research

authors： Namiki S,Kanzaki R

更新日期：2018-12-01 00:00:00

abstract：:The pineal gland structure and ultrastructure in the Northern (Blarina brevicauda) and Southern short-tailed shrew (Blarina carolinensis) are described by light and electron microscopy. Results observed were similar to other mammals of Insectivora described previously, specifically, the hedgehog (Erinaceus europaeus) ...

journal_title：Cell and tissue research

authors： Manno FAM,Lau C

更新日期：2018-12-01 00:00:00

abstract：:Recent studies demonstrated the expression of the insulin receptor (InsR) and its functional interaction with the transient receptor potential vanilloid type 1 receptor (TRPV1) in primary sensory neurons (PSNs). The present study was undertaken to reveal the target-specific expression of the InsR and its co-localizati...

journal_title：Cell and tissue research

authors： Lázár BA,Jancsó G,Nagy I,Horváth V,Sántha P

更新日期：2018-11-01 00:00:00

abstract：:The present study attempts to elucidate the role of TRPV1 cation channel receptor on primary repair in an incision-wounded mouse cornea in vivo. Previous study revealed that blocking TRPV1 suppressed myofibroblast formation and expression of transforming growth factor β1 (TGFβ1) in cultured keratocytes or ocular fibro...

journal_title：Cell and tissue research

authors： Nidegawa-Saitoh Y,Sumioka T,Okada Y,Reinach PS,Flanders KC,Liu CY,Yamanaka O,Kao WW,Saika S

更新日期：2018-11-01 00:00:00

abstract：:The stem cells with their distinct ability of self-renewal and differentiation are considered an innovation in wound healing. However, there is lack of studies comparing the differential effect of the type and administration route of stem cells in the wound healing context. Thus, the current study has been designed to...

journal_title：Cell and tissue research

authors： Aboulhoda BE,Abd El Fattah S

更新日期：2018-11-01 00:00:00

abstract：:Survival of mesenchymal stem cells (MSCs) against oxidative stress and inflammation is vital for effective stem cell therapy. The reactive oxygen species (ROS) result in apoptosis and release of inflammatory mediators. Adipose-derived stem cells (ASCs) have shown promise for stem cell therapy owing to their anti-infla...

journal_title：Cell and tissue research

authors： Bhatti FUR,Kim SJ,Yi AK,Hasty KA,Cho H

更新日期：2018-10-01 00:00:00

abstract：:The desert locust Schistocerca gregaria is a major agricultural pest in North Africa and the Middle East. As such, it has been intensely studied, in particular with respect to population dynamics, sensory processing, feeding behavior flight and locomotor control, migratory behavior, and its neuroendocrine system. Bein...

journal_title：Cell and tissue research

authors： von Hadeln J,Althaus V,Häger L,Homberg U

更新日期：2018-10-01 00:00:00

abstract：:The published online version contains mistake in Title and in Acknowledgement section. Please find below for the needed corrections. ...

journal_title：Cell and tissue research

authors： Pan J,Liu M,Chen T,Cheng Y,Wu X

更新日期：2018-10-01 00:00:00

abstract：:17beta-estradiol (E2) is important for crustacean ovarian development. This study aims to investigate the distribution and change pattern of E2 in the ovary, hepatopancreas, thoracic ganglion and brain ganglion as well as Vg-mRNA expression level during ovarian development of Chinese mitten crab Eriocheir sinensis. Re...

journal_title：Cell and tissue research

authors： Pan J,Liu M,Chen T,Cheng Y,Wu X

更新日期：2018-08-01 00:00:00

abstract：:Apart from the characteristic and progressive motor- and movement-related problems, Parkinson's disease (PD) patients also suffer from several non-motor symptoms, including gastrointestinal dysfunction. The fact that the enteric nervous system (ENS) controls motility and that one of the typical PD hallmarks, α-synucle...

journal_title：Cell and tissue research

authors： Shannon K,Vanden Berghe P

更新日期：2018-07-01 00:00:00

abstract：:It is a well-established fact that the sympathetic, parasympathetic and enteric nervous systems are affected at early stages in Parkinson's disease (PD). However, it is not yet clarified whether the earliest pathological events preferentially occur in any of these three divisions of the autonomic nervous system (ANS)....

journal_title：Cell and tissue research

authors： Orimo S,Ghebremedhin E,Gelpi E

更新日期：2018-07-01 00:00:00

abstract：:Neuroblastoma is an embryonal malignancy that affects normal development of the adrenal medulla and paravertebral sympathetic ganglia in early childhood. Extensive studies have revealed the molecular characteristics of human neuroblastomas, including abnormalities at genome, epigenome and transcriptome levels. However...

journal_title：Cell and tissue research

authors： Tsubota S,Kadomatsu K

更新日期：2018-05-01 00:00:00

abstract：:Neuroblastoma, a malignancy of the developing peripheral nervous system that affects infants and young children, is a complex genetic disease. Over the past two decades, significant progress has been made toward understanding the genetic determinants that predispose to this often lethal childhood cancer. Approximately...

journal_title：Cell and tissue research

authors： Ritenour LE,Randall MP,Bosse KR,Diskin SJ

更新日期：2018-05-01 00:00:00

abstract：:New genome-editing approaches, such as the CRISPR/Cas system, have opened up great opportunities to insert or delete genes at targeted loci and have revolutionized genetics in model organisms like the zebrafish. The Cre-loxp recombination system is widely used to activate or inactivate genes with high spatial and temp...

journal_title：Cell and tissue research

authors： Kesavan G,Hammer J,Hans S,Brand M

更新日期：2018-04-01 00:00:00

abstract：:Andersen's syndrome (AS) is a rare autosomal disorder that has been defined by the triad of periodic paralysis, cardiac arrhythmia, and developmental anomalies. AS has been directly linked to over 40 different autosomal dominant negative loss-of-function mutations in the KCNJ2 gene, encoding for the tetrameric strong ...

journal_title：Cell and tissue research

authors： Simkin D,Robin G,Giuliano S,Vukolic A,Moceri P,Guy N,Wagner KD,Lacampagne A,Allard B,Bendahhou S

更新日期：2018-02-01 00:00:00

abstract：:Three-dimensional cultures of primary epithelial cells including organoids, enteroids and epithelial spheroids have become increasingly popular for studies of gastrointestinal development, mucosal immunology and epithelial infection. However, little is known about the behavior of these complex cultures in their three-...

journal_title：Cell and tissue research

authors： Sebrell TA,Sidar B,Bruns R,Wilkinson RA,Wiedenheft B,Taylor PJ,Perrino BA,Samuelson LC,Wilking JN,Bimczok D

更新日期：2018-02-01 00:00:00

abstract：:Notch signaling is evolutionarily conserved from Drosophila to human. It plays critical roles in neural stem cell maintenance and neurogenesis in the embryonic brain as well as in the adult brain. Notch functions greatly depend on careful regulation and cross-talk with other regulatory mechanisms. Deregulation of Notc...

journal_title：Cell and tissue research

authors： Zhang R,Engler A,Taylor V

更新日期：2018-01-01 00:00:00

abstract：:Neural stem and progenitor cells produce one of the most remarkable organs in nature, the human brain. Among neural stem cell progeny, post-mitotic neurons are likewise remarkably diverse. Single-cell transcriptomic approaches are now cataloging a long-sought-after molecular taxonomy of neuronal diversity in the brain...

journal_title：Cell and tissue research

authors： Harbom LJ,Michel N,McConnell MJ

更新日期：2018-01-01 00:00:00

abstract：:Homeostatic cell turnover has been extensively characterized in mammals. In their adult tissues, lost or aging differentiated cells are replenished by a self-renewing cohort of stem cells. The stem cells have been particularly well studied in the intestine and are clearly identified by the expression of marker genes i...

journal_title：Cell and tissue research

authors： Mashanov V,Zueva O,Mashanova D,García-Arrarás JE

更新日期：2017-12-01 00:00:00

abstract：:In cattle, the oviduct plays a major role in the reproductive process; however, molecular control of oviduct receptivity to the embryo is poorly understood. A model for receptivity based on size of the pre-ovulatory follicle (POF) was used to compare oviductal morphology, cellular proliferation, and candidate transcri...

journal_title：Cell and tissue research

authors： Gonella-Diaza AM,Mesquita FS,da Silva KR,de Carvalho Balieiro JC,Dos Santos NP,Pugliesi G,de Francisco Strefezzi R,Binelli M

更新日期：2017-11-01 00:00:00

abstract：:Clusterin (CLU) is an extracellular chaperone protein that is implicated in diverse physiological and pathophysiological cellular processes. CLU expression is upregulated in response to cellular stress and under certain conditions, such as neurodegenerative disease and cancer. CLU primarily functions as a chaperone th...

journal_title：Cell and tissue research

authors： Lee S,Shin JO,Sagong B,Kim UK,Bok J

更新日期：2017-10-01 00:00:00

abstract：:Sox2-expressing stem/progenitor cells in the anterior lobe of the pituitary gland form two types of micro-environments (niches): the marginal cell layer and dense cell clusters in the parenchyma. In relation to the mechanism of regulation of niches, juxtacrine signaling via ephrin and its receptor Eph is known to play...

journal_title：Cell and tissue research

authors： Yoshida S,Kato T,Kanno N,Nishimura N,Nishihara H,Horiguchi K,Kato Y

更新日期：2017-10-01 00:00:00

abstract：:There is general consensus that enteroendocrine cells, EEC, containing the enteric hormone cholecystokinin (CCK) are confined to the small intestine and predominate in the duodenum and jejunum. Contrary to this, EEC that express the gene for CCK have been isolated from the large intestine of the mouse and there is evi...

journal_title：Cell and tissue research

authors： Fakhry J,Wang J,Martins P,Fothergill LJ,Hunne B,Prieur P,Shulkes A,Rehfeld JF,Callaghan B,Furness JB

更新日期：2017-08-01 00:00:00

abstract：:Mast cells (MCs) and airway nerves play an important role in allergic asthma. However, little is known about the MCs and their interaction with airway nerves during allergic airway inflammation. This study aims to investigate the distribution and proliferation of MC populations in different lung compartments, along wi...

journal_title：Cell and tissue research

authors： Schmit D,Le DD,Heck S,Bischoff M,Tschernig T,Herr C,Beisswenger C,Kobelt P,Lepper PM,Chung KF,Bals R,Dinh QT

更新日期：2017-08-01 00:00:00

abstract：:Renovascular hypertension (RVH) is a progressive disease, leading to chronic kidney disease when untreated and no specific treatment is available. Therefore, development of new therapeutic modalities is imperative. RVH is triggered by renal artery stenosis and subsequent renin-angiotensin-aldosterone system activation...

journal_title：Cell and tissue research

authors： Lira R,Oliveira M,Martins M,Silva C,Carvalho S,Stumbo AC,Cortez E,Verdoorn K,Einicker-Lamas M,Thole A,de Carvalho L

更新日期：2017-08-01 00:00:00

abstract：:Our aim is to gain insight into the mechanisms underlying the anti-atrophic effects of leucine, namely, the way that this amino acid can restrain the up-regulation of MuRF1 and Mafbx/Atrogin-1 in muscle atrophy. Male rats received dietary leucine supplementation for 1-3 days, during which time their hind limbs were im...

journal_title：Cell and tissue research

authors： Baptista IL,Silvestre JG,Silva WJ,Labeit S,Moriscot AS

更新日期：2017-08-01 00:00:00

abstract：:Growing numbers of translational genomics studies are based on the highly efficient and versatile zebrafish (Danio rerio) vertebrate model. The increasing types of zebrafish models have improved our understanding of inherited kidney diseases, since they not only display pathophysiological changes but also give us the ...

journal_title：Cell and tissue research

authors： Schenk H,Müller-Deile J,Kinast M,Schiffer M

更新日期：2017-07-01 00:00:00

abstract：:The kidney is an organ involved in cross talk with many human organs. The link between the immune system and the kidney has been studied in some detail, although data precisely elucidating their interaction are sparse, in particular with regard to the function of the kidney filter apparatus. Current research suggests ...

journal_title：Cell and tissue research

authors： Hahm E,Peev V,Reiser J

更新日期：2017-07-01 00:00:00

abstract：:Exposure to maternal diabetes during fetal growth is a risk factor for the development of type II diabetes (T2D) in later life. Discovery of the mechanisms involved in this association should provide valuable background for therapeutic treatments. Early embryogenesis involves epigenetic changes including histone modif...

journal_title：Cell and tissue research

authors： Chen ACH,Lee YL,Fong SW,Wong CCY,Ng EHY,Yeung WSB

更新日期：2017-06-01 00:00:00